diff --git a/debian/patches/debian/test-sysroot-Skip-on-s390x-by-default.patch b/debian/patches/debian/test-sysroot-Skip-on-s390x-by-default.patch
new file mode 100644
index 00000000..6dcef390
--- /dev/null
+++ b/debian/patches/debian/test-sysroot-Skip-on-s390x-by-default.patch
@@ -0,0 +1,30 @@
+From: Simon McVittie <smcv@debian.org>
+Date: Tue, 6 Dec 2022 10:59:33 +0000
+Subject: test-sysroot: Skip on s390x by default
+
+This test regularly fails on the buildds, but I cannot reproduce the
+failure on a porterbox.
+
+Bug: https://github.com/ostreedev/ostree/issues/2527
+Bug-Debian: https://bugs.debian.org/1025532
+Forwarded: not-needed
+---
+ tests/test-sysroot.js | 5 +++++
+ 1 file changed, 5 insertions(+)
+
+diff --git a/tests/test-sysroot.js b/tests/test-sysroot.js
+index d4f67ef..0855b3d 100755
+--- a/tests/test-sysroot.js
++++ b/tests/test-sysroot.js
+@@ -38,6 +38,11 @@ function libtestExec(shellCode) {
+     proc.wait_check(null);
+ }
+ 
++if (GLib.getenv('DEB_HOST_ARCH') === 's390x' && !GLib.getenv('DEB_ALLOW_FLAKY_TESTS')) {
++    print('1..0 # SKIP https://bugs.debian.org/1025532');
++    imports.system.exit(0);
++}
++
+ print('1..1')
+ 
+ libtestExec('setup_os_repository archive syslinux');
diff --git a/debian/patches/series b/debian/patches/series
index 82f25e2b..895738c4 100644
--- a/debian/patches/series
+++ b/debian/patches/series
@@ -1,2 +1,3 @@
-debian/Skip-test-pull-repeated-during-CI.patch
 configure-use-pkg-config-with-newer-gpgme-and-gpg-error.patch
+debian/Skip-test-pull-repeated-during-CI.patch
+debian/test-sysroot-Skip-on-s390x-by-default.patch
diff --git a/debian/tests/control b/debian/tests/control
index 28691e70..f619ebc9 100644
--- a/debian/tests/control
+++ b/debian/tests/control
@@ -1,4 +1,9 @@
-Tests: flaky
+Tests: flaky-concurrency
+Restrictions: flaky
+Depends: gnome-desktop-testing, ostree-tests
+
+Tests: flaky-sysroot
+Architecture: s390x
 Restrictions: flaky
 Depends: gnome-desktop-testing, ostree-tests
 
diff --git a/debian/tests/flaky b/debian/tests/flaky-concurrency
old mode 100644
new mode 100755
similarity index 100%
rename from debian/tests/flaky
rename to debian/tests/flaky-concurrency
diff --git a/debian/tests/flaky-sysroot b/debian/tests/flaky-sysroot
new file mode 100644
index 00000000..8865f9ec
--- /dev/null
+++ b/debian/tests/flaky-sysroot
@@ -0,0 +1,12 @@
+#!/bin/sh
+
+set -e
+exec 2>&1
+
+unset ftp_proxy
+unset http_proxy
+unset https_proxy
+unset no_proxy
+export DEB_ALLOW_FLAKY_TESTS=1
+
+exec gnome-desktop-testing-runner libostree/test-sysroot.js.test
diff --git a/debian/tests/gnome-desktop-testing b/debian/tests/gnome-desktop-testing
index e4346cac..b041ae0d 100755
--- a/debian/tests/gnome-desktop-testing
+++ b/debian/tests/gnome-desktop-testing
@@ -11,7 +11,9 @@ unset http_proxy
 unset https_proxy
 unset no_proxy
 
-tests="$(gnome-desktop-testing-runner -l libostree | while read -r t; do
+namespace=libostree/
+
+tests="$(gnome-desktop-testing-runner -l "$namespace" | while read -r t; do
 	t="${t%% *}"
 
 	case "$t" in
@@ -20,11 +22,24 @@ tests="$(gnome-desktop-testing-runner -l libostree | while read -r t; do
 			# https://github.com/ostreedev/ostree/issues/1620
 			continue
 			;;
+
+		(libostree/test-sysroot.js.test)
+			# https://bugs.debian.org/1025532
+			# https://github.com/ostreedev/ostree/issues/2527
+			if [ "${DEB_HOST_ARCH-}" = s390x ] || [ "$(uname -m)" = s390x ]; then
+				continue
+			fi
+			;;
 	esac
 
 	echo "$t"
 done)"
 
+if [ -z "$tests" ]; then
+	echo "Error: no installed-tests found matching $namespace" >&2
+	exit 1
+fi
+
 # Deliberately word-splitting
 # shellcheck disable=SC2046
 exec gnome-desktop-testing-runner $tests